beta Actin antibody (N-Term)
Quick Overview for beta Actin antibody (N-Term) (ABIN1105241)
Target
See all beta Actin (ACTB) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- N-Term
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Specificity
- This antibody reacts to Actin beta.
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Purification
- Purified
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Immunogen
- Peptide DDIAALVVDNGDG derived from human b-Actin, N-terminal conjugated to KLH.
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Isotype
- IgG2b
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1,0 mg/mL
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Buffer
- PBS with 0.02 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- beta Actin (ACTB) (Actin, beta (ACTB))
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Alternative Name
- Actin beta / ACTB
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Background
- The primary site of action of cytochalasin B on cell motility processes is beta-actin. Habets et al. (1992) generated hybrids that harbor only specific regions of human chromosome 7 and assigned the ACTB locus to 7p15-p12. ACTB and the other assigned beta-actin-related sequences are dispersed over at least four different chromosomes including one locus assigned to the X chromosome. A mutation of beta-actin that alters depolymerization dynamics is associated with autosomal dominant developmental malformations, deafness, and dystonia.Synonyms: Actin cytoplasmic 1, Beta-Actin
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Gene ID
- 60
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NCBI Accession
- NP_001092
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UniProt
- P60709
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Pathways
- Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Maintenance of Protein Location, Phototransduction
Target
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