BHLHE22 antibody (N-Term)

Catalog No. ABIN1105525

This Rabbit Polyclonal antibody specifically detects BHLHE22 in WB. It exhibits reactivity toward Human, Mouse, Rat, Zebrafish (Danio rerio), Cow and Chicken.

Quick Overview for BHLHE22 antibody (N-Term) (ABIN1105525)

Target: BHLHE22 (Basic Helix-Loop-Helix Family, Member E22 (BHLHE22))

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BHLHE22 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BHLHE22 Antibody

Binding Specificity: N-Term

Sequence: LPAGAALCLK YGESASRGSV AESSGGEQSP DDDSDGRCEL VLRAGVADPR

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, ZebrafishSpecies reactivity (tested):Human

Purification: Purified using peptide immunoaffinity column

Immunogen: The immunogen for anti-BHLHB5 antibody: synthetic peptide directed towards the N terminal of human BHLHB5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Target Details for BHLHE22

Target: BHLHE22 (Basic Helix-Loop-Helix Family, Member E22 (BHLHE22))

Alternative Name: BHLHB5 / BHLHE22

Background: BHLHB5 is a member of family of basic helix-loop-helix (bHLH) transcription factors. Members of this family have been implicated in many aspects of neural development, including cell growth, differentiation, and cell migration. BHLHB5 inhibits DNA binding of TCF3/E47 homodimers and TCF3 (E47)/NEUROD1 heterodimers and acts as a strong repressor of Neurod1 and Myod-responsive genes, probably by heterodimerization with class a basic helix-loop-helix factors. Despite the presence of an intact basic domain, does not bind to DNA.Synonyms: Class B basic helix-loop-helix protein 5, Class E basic helix-loop-helix protein 22, TNRC20, Trinucleotide repeat-containing gene 20 protein

Gene ID: 27319

NCBI Accession: NP_689627