IL13RA2 antibody

Catalog No. ABIN1106072

Product Details anti-IL13RA2 Antibody

Target: IL13RA2 (Interleukin 13 Receptor, alpha 2 (IL13RA2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL13RA2 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: Recognizes the soluble antigen. Recognizes the IL-13 receptor a2 (IL-13 Ra2), a 74 kDa protein. Tested on monocyte activation (Secretion IL-6).

Purification: Ion Exchange Chromatography.

Sterility: 0.22 μm filtered

Immunogen: IL-13Ra2 transfected CHO cell line. Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells.

Clone: B-D13

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate-buffered saline without carrier and preservatives. This prodcut is sterile-filtered through 0.22 μm and treated to remove endotoxins.

Preservative: Without preservative

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for IL13RA2

Target: IL13RA2 (Interleukin 13 Receptor, alpha 2 (IL13RA2))

Alternative Name: CD213a2 / IL13RA2 (IL13RA2 Products)

Background: IL-13 receptor alpha 2 belongs to the type I cytokine receptor family, Contains 1 fibronectin type-III domain, Binds as a monomer with high affinity to interleukin-13 (IL13), but not to interleukin-4 (IL4). The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding. The box 1 motif is required for JAK interaction and/or activation.Synonyms: IL-13R-alpha-2, IL-13RA-2, IL13 receptor alpha-2, IL13R, IL13RA2, Interleukin-13 receptor alpha-2 chain, Interleukin-13-binding protein

Gene ID: 3598

NCBI Accession: NP_000631

UniProt: Q14627