Desmoglein 2 antibody (Extracellular Domain)
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- Target See all Desmoglein 2 (DSG2) Antibodies
- Desmoglein 2 (DSG2)
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Binding Specificity
- Extracellular Domain
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Desmoglein 2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunoprecipitation (IP)
- Specificity
- The monoclonal antibody 6D8 recognizes the extracellular domain of human desmoglein-2. Does not cross react with desmoglein-1 and desmoglein-3.
- Cross-Reactivity (Details)
- Species reactivity (tested):Human
- Purification
- Protein G
- Immunogen
- Extracellular EC4 domain
- Clone
- 6D8
- Isotype
- IgG1
- Top Product
- Discover our top product DSG2 Primary Antibody
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anti-Desmoglein 2 (DSG2) (N-Term) antibody
DSG2 Reactivity: Human WB, IF, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
anti-Desmoglein 2 (DSG2) (AA 72-121) antibodyDSG2 Reactivity: Human, Rat, Mouse, Monkey WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Desmoglein 2 (DSG2) (N-Term) antibodyDSG2 Reactivity: Human, Rat, Mouse, Cow, Dog, Pig, Guinea Pig, Horse, Rabbit WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Desmoglein 2 (DSG2) (AA 275-533) antibodyDSG2 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Desmoglein 2 (DSG2) (AA 183-331) antibodyDSG2 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Desmoglein 2 (DSG2) (AA 145-216), (N-Term) antibodyDSG2 Reactivity: Human WB, FACS Host: Rabbit Polyclonal RB16855 unconjugated
anti-Desmoglein 2 (DSG2) (AA 37-164) antibodyDSG2 Reactivity: Human WB, IF, IP, ICC Host: Mouse Monoclonal 10D2 unconjugated
anti-Desmoglein 2 (DSG2) (N-Term) antibodyDSG2 Reactivity: Human, Rat, Mouse WB Host: Rabbit Polyclonal unconjugated
anti-Desmoglein 2 (DSG2) (AA 51-150) antibodyDSG2 Reactivity: Human, Rat, Mouse WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Desmoglein 2 (DSG2) antibodyDSG2 Reactivity: Human WB, IF, FACS Host: Mouse Monoclonal 6D8 unconjugated
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.1 mg/mL
- Buffer
- PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- Desmoglein 2 (DSG2)
- Alternative Name
- Desmoglein-2 (DSG2 Products)
- Background
- Desmogleins and desmocollins are members of the cadherin family of transmembrane proteins that together make up the core of the desmosome, a structure that provides transmembrane strength to tissues undergoing mechanical stress. The desmosomal cadherins, desmogleins and desmocollins, mediate calcium-dependent cell-cell adhesion by forming homotypic and heterotypic interactions with one another. The multiprotein desmosomal complex also includes the cytoplasmic desmosomal plaque proteins plakoglobin, phakophilins, and desmoplakin, which bind to the intracellular domain of the desmogleins and function to anchor the keratin intermediate filament network to site of cell-cell contacts.Synonyms: CDHF5, Cadherin family member 5, DSG2, HDGC
- Gene ID
- 1829
- NCBI Accession
- NP_001934
- UniProt
- Q14126
- Pathways
- Cell-Cell Junction Organization
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