DPYSL3 antibody (C-Term)

Catalog No. ABIN1107016

This Rabbit Polyclonal antibody specifically detects DPYSL3 in WB, IHC (fro) and EIA. It exhibits reactivity toward Human.

Quick Overview for DPYSL3 antibody (C-Term) (ABIN1107016)

Target: DPYSL3 (Dihydropyrimidinase-Like 3 (DPYSL3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DPYSL3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Product Details anti-DPYSL3 Antibody

Binding Specificity: C-Term

Specificity: Reacts with 65 kDa CRMP-4. This antibody does not react with CRMP-1, CRMP-2, CRMP-3 or CRMP-5.

Cross-Reactivity (Details): Species reactivity (tested):Human, Rat, Mouse.

Purification: Affinity Chromatography on Protein A

Immunogen: A 15 residue synthetic peptide derived from C-terminal domain of Human Collapsing- Response Mediator.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Restore in distilled water.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store the antibody at -20 °C. Store reconstituted antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for DPYSL3

Target: DPYSL3 (Dihydropyrimidinase-Like 3 (DPYSL3))

Alternative Name: DPYSL3 / CRMP4

Background: The collapsin response mediator protein (CRMP) family of five cytosolic phosphoproteins are highly expressed throughout brain development. The functions of CRMPs encompass signal transduction in developmental guidance cues as well as multiple cellular and molecular events involved in apoptosis/proliferation, cell migration, and differentiation. In the adult brain, the expression of CRMPs is dramatically downregulated. However, CRMPs remain expressed in structures that retain their capacity for differentiation and plasticity. The expression of CRMPs is altered in neurodegenerative diseases, and these proteins may have a role in the physiopathology of the adult nervous system.Synonyms: CRMP-4, Collapsin response mediator protein 4, DRP-3, DRP3, Dihydropyrimidinase-related protein 3, TUC-4, ULIP, ULIP-1, ULIP1, Unc-33-like phosphoprotein 1

Gene ID: 1809

NCBI Accession: NP_001184223