Lactoferrin antibody

Catalog No. ABIN1107996

This anti-Lactoferrin antibody is a Mouse Monoclonal antibody detecting Lactoferrin in WB and EIA. Suitable for Cow. This Primary Antibody has been cited in 2+ publications.

Quick Overview for Lactoferrin antibody (ABIN1107996)

Target: Lactoferrin (LTF) (Lactotransferrin (LTF))

Reactivity: Cow

Host: Mouse

Clonality: Monoclonal

Conjugate: This Lactoferrin antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: 5F12-1-2

Product Details anti-Lactoferrin Antibody

Purification: Protein G purified

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2 - 8 °C.

References for anti-Lactoferrin antibody (ABIN1107996)

Shimazaki, Kamio, Nam, Harakawa, Tanaka, Omata, Saito, Kumura, Mikawa, Igarashi, Suzuki: "Structural and immunochemical studies on bovine lactoferrin fragments." in: Advances in experimental medicine and biology, Vol. 443, pp. 41-8, (1998) (PubMed).

Shimazaki, Nam, Harakawa, Tanaka, Omata, Saito, Kumura, Mikawa, Igarashi, Suzuki: "Monoclonal antibody against bovine Lactoferricin and its epitopic site." in: The Journal of veterinary medical science / the Japanese Society of Veterinary Science, Vol. 58, Issue 12, pp. 1227-9, (1997) (PubMed).

Target Details for Lactoferrin

Target: Lactoferrin (LTF) (Lactotransferrin (LTF))

Alternative Name: Lactotransferrin

Background: Lactoferricin B is derived by enzymatic cleavage of lactoferrin which is a member of the transferrin family of metal-binding proteins found in milk and other secretory fluids and also in blood. Cleavage by pepsin of bovine lactoferrin leads to the release of Lactoferricin B (aminoacid 17-41). This peptide is highly basic, possessing five Arg (R) and three Lys (K) residues. In addition, a number of Trp (W) and Phe (F) aromatic residues are present. The two Cys (C) residues from lactoferricin B form a disulfide bond, generating an almost completely cyclical peptide. Nevertheless, the disulfide bond is not required for the antimicrobial potency. Several studies have shown that Lactoferricin B has a broad-spectrum activity against various Gram-positive and Gram-negative bacteria. In addition the peptide has been shown to have antifungal, antiviral and antitumour activity and to bind lipopolysaccharides (LPS, endotoxin). Moreover, it is known to stimulate the adaptive immune response and has anti-inflammatory properties. Lactoferricin B belongs to a large group of cationic antimicrobial peptides.Synonyms: EC=3.4.21, LF, LTF, Lactoferrin, Talalactoferrin

Gene ID: 9913

UniProt: P24627

Pathways: Transition Metal Ion Homeostasis