Lactoferrin antibody

Catalog No. ABIN1107998

The Rabbit Polyclonal anti-Lactoferrin antibody has been validated for WB, IP and EIA. It is suitable to detect Lactoferrin in samples from Cow.

Quick Overview for Lactoferrin antibody (ABIN1107998)

Target: Lactoferrin (LTF) (Lactotransferrin (LTF))

Reactivity: Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lactoferrin antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Product Details anti-Lactoferrin Antibody

Specificity: This antibody detects Bovine Lactoferrin. Other species not tested.

Purification: Protein A Chromatography

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: PBS, 0.02 % Sodium Azide, 0.1 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 2-8 °C.

Target Details for Lactoferrin

Target: Lactoferrin (LTF) (Lactotransferrin (LTF))

Alternative Name: Lactotransferrin

Background: Lactoferrin is an approximately 80 kDa glycoprotein which was first isolated from milk and found in epithelia and most body fluids and secretions. Lactoferrin is secreted in plasma by neutrophils. Its plasma concentration represents a positive relation to the total pool of neutrophils and the rate of neutrophil turnover. In inflammation lactoferrin is released from secondary granules of neutrophilic leukocytes into the extracellular medium. Therefore the extracellular lactoferrin concentration can be used as an index for neutrophil activation. Lactoferrin is able to strongly bind to iron and considered to have antibacterial properties. Human lactoferrin binds to bacterial products through its highly positively charged N terminus and kills various bacteria most probably by inducing intracellular changes in these bacteria without affecting the membrane permeability. Lactoferrin also plays a role in signal transduction, immunomodulation and has antiadhesive, anticancer, antiviral activity.Synonyms: EC=3.4.21, LF, LTF, Lactoferrin, Talalactoferrin

Gene ID: 280846

NCBI Accession: NP_851341

UniProt: P24627

Pathways: Transition Metal Ion Homeostasis