LY86 antibody

Catalog No. ABIN1108079

The Rat Monoclonal anti-LY86 antibody has been validated for FACS and Func. It is suitable to detect LY86 in samples from Mouse.

Quick Overview for LY86 antibody (ABIN1108079)

Target: LY86 (Lymphocyte Antigen 86 (LY86))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This LY86 antibody is un-conjugated

Application: Flow Cytometry (FACS), Functional Studies (Func)

Clone: MD113

Product Details anti-LY86 Antibody

Specificity: The monoclonal antibody MD113 reacts with mouse MD-1. The antibody is antagonistic in LPS-induced B-cell proliferation and B7.2 up-regulation.

Cross-Reactivity (Details): Species reactivity (tested):Mouse

Purification: Protein G

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for LY86

Target: LY86 (Lymphocyte Antigen 86 (LY86))

Alternative Name: LY86 / MD-1

Background: MD-1 (22-25 kD) is an extracellular protein associated with the extracellular domain of RP105. The latter is a type 1 transmembrane protein with leucine-rich repeats. RP105 is similar to Drosophila Toll. MD-1 associated with RP105 (similar to TLR4/MD-2) appears to be an essential molecule that helps RP105 on B-cells to signal to LPS.Synonyms: Lymphocyte antigen 86, MD1

Gene ID: 17084

Pathways: Toll-Like Receptors Cascades