POU1F1 antibody (C-Term)

Catalog No. ABIN1108699

This Rabbit Polyclonal antibody specifically detects POU1F1 in WB and IHC (p). It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Pig and Chicken.

Quick Overview for POU1F1 antibody (C-Term) (ABIN1108699)

Target: POU1F1 (POU Class 1 Homeobox 1 (POU1F1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Pig, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POU1F1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-POU1F1 Antibody

Binding Specificity: C-Term

Sequence: QEIMRMAEEL NLEKEVVRVW FCNRRQREKR VKTSLNQSLF SISKEHLECR

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Dog, Bovine, Pig, ChickenSpecies reactivity (tested):Human

Purification: Purified on peptide immunoaffinity column

Immunogen: The immunogen for anti-POU1F1 antibody: synthetic peptide directed towards the C terminal of human POU1F1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Add 50 μL of distilled water

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the lyophised antibody at -20 °C for up to one year. Store reconstitued antibody undiluted for one month or in aliquots at -20 °C long term.

Expiry Date: 12 months

Target Details for POU1F1

Target: POU1F1 (POU Class 1 Homeobox 1 (POU1F1))

Alternative Name: POU1F1

Background: PIT1 is a pituitary-specific transcription factor responsible for pituitary development and hormone expression in mammals and is a member of the POU family of transcription factors that regulate mammalian development. The POU family is so named because the first 3 members identified were PIT1 and OCT1 of mammals, and Unc-86 of C. elegans. PIT1 contains 2 protein domains, termed POU-specific and POU-homeo, which are both necessary for high affinity DNA binding on genes encoding growth hormone and prolactin. PIT1 is also important for regulation of the genes encoding prolactin and thyroid-stimulating hormone beta subunit by thyrotropin-releasing hormone and cyclic AMP.Synonyms: GHF-1, GHF1, Growth hormone factor 1, PIT-1, PIT1, Pituitary-specific positive transcription factor 1

Gene ID: 5449

NCBI Accession: NP_000297

Pathways: Regulation of Carbohydrate Metabolic Process