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PROS1 antibody (FITC)

The Rat Monoclonal anti-PROS1 antibody has been validated for WB. It is suitable to detect PROS1 in samples from Human.
Catalog No. ABIN1108757

Quick Overview for PROS1 antibody (FITC) (ABIN1108757)

Target

See all PROS1 (PROS) Antibodies
PROS1 (PROS) (Protein S (PROS))

Reactivity

  • 87
  • 28
  • 25
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Host

  • 67
  • 13
  • 7
  • 5
  • 4
Rat

Clonality

  • 82
  • 14
Monoclonal

Conjugate

  • 54
  • 8
  • 8
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PROS1 antibody is conjugated to FITC

Application

  • 71
  • 32
  • 27
  • 18
  • 17
  • 13
  • 8
  • 6
  • 6
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB)

Clone

PS7
  • Cross-Reactivity (Details)

    Species reactivity (tested):Human.

    Purification

    Protein G Chromatography

    Isotype

    IgG2a
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Concentration

    0.1 mg/mL

    Buffer

    PBS, 0.02 % Sodium Azide, 1 % BSA

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C

    Storage Comment

    Store undiluted at 2-8 °C.
  • Target

    PROS1 (PROS) (Protein S (PROS))

    Background

    In humans, PS is mainly synthesized by hepatocytes. Mature PS has a modular structure consisting of a Gla-domain containing a short aromatic stack, a region sensitive to cleavage by thrombin and factor Xa , 4 epidermal growth factor (EGF)-like domains, and a sex hormone-binding globulin-like region. The biologic function of PS thought to be of primary importance is its ability to enhance Activated Protein C-dependent proteolytic inactivation of factors Va and VIIIa, which are respectively the cofactors in the pro-thrombinase and tenase complexes of the coagulation cascade. In this way, PS plays an important role in regulating thrombin generation, and therefore controlling procoagulant activity. Crucial to the APC-dependent functions of PS is the high-affinity interaction between PS and negatively charged phospholipid surfaces, conferred by calcium-induced folding of the amino-terminal Gla-domain.Synonyms: PROS, Vitamin K-dependent protein S

    UniProt

    P07225
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