RAD21 antibody

Catalog No. ABIN1108819

This Rabbit Polyclonal antibody specifically detects RAD21 in WB, IHC (fro) and EIA. It exhibits reactivity toward Human.

Quick Overview for RAD21 antibody (ABIN1108819)

Target: RAD21 (RAD21 Homolog (RAD21))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAD21 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Product Details anti-RAD21 Antibody

Specificity: Reacts with 71 kDa RAD21 protein.

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse, Rat.

Purification: Affinity Chromatography on Protein A

Immunogen: Synthetic peptide derived from Internal domain of Human RAD21

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Restore in distilled water.

Buffer: 0.1 M Tris, 0.1 M Glycine and 2 % Sucrose, None

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Prior to reconstitution store the antibody at-20 °C. Store reconstituted antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for RAD21

Target: RAD21 (RAD21 Homolog (RAD21))

Alternative Name: RAD21

Background: RAD21 is highly similar to the gene product of Schizosaccharomyces pombe rad21, a protein involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells.Synonyms: Double-strand-break repair protein rad21 homolog, HR21, KIAA0078, NXP1, Nuclear matrix protein 1, SCC1 homolog

Gene ID: 5885

NCBI Accession: NP_006256

UniProt: O60216

Pathways: Positive Regulation of Endopeptidase Activity