RRN3 antibody (C-Term)

Catalog No. ABIN1108907

The Rabbit Polyclonal anti-RRN3 antibody has been validated for WB. It is suitable to detect RRN3 in samples from Human, Mouse, Rat, Cow, Dog and Chicken.

Quick Overview for RRN3 antibody (C-Term) (ABIN1108907)

Target: RRN3 (RRN3 RNA Polymerase I Transcription Factor (RRN3))

Reactivity: Human, Mouse, Rat, Cow, Dog, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RRN3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RRN3 Antibody

Binding Specificity: C-Term

Sequence: KKDIVEDEDD DFLKGEVPQN DTVIGITPSS FDTHFRSPSS SVGSPPVLYM

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Dog, Bovine, ChickenSpecies reactivity (tested):Human

Purification: Purified using peptide immunoaffinity column

Immunogen: he immunogen for anti-RRN3 antibody: synthetic peptide directed towards the C terminal of human RRN3.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Target Details for RRN3

Target: RRN3 (RRN3 RNA Polymerase I Transcription Factor (RRN3))

Alternative Name: RRN3

Background: RRN3 is RNA polymerase I-specific transcription initiation factor. Phosphorylation of RRN3 by MAPK cascades links cell signaling with the control of gene expression, namely results in rRNA synthesis in turn cell growth.Synonyms: RNA polymerase I-specific transcription initiation factor RRN3, TIF-IA, TIFIA, Transcription initiation factor IA

Gene ID: 54700

NCBI Accession: NP_060897

Pathways: Negative Regulation of intrinsic apoptotic Signaling