The Rabbit Polyclonal anti-TFCP2 antibody has been validated for WB. It is suitable to detect TFCP2 in samples from Human, Mouse, Rat, Dog, Cow, Chicken and Xenopus laevis.
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Reconstitution
Add 50 μL of distilled water
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Store the lyophised antibody at -20 °C for up to one year. Store reconstitued antibody undiluted for one month or in aliquots at -20 °C long term
Expiry Date
12 months
Target
TFCP2
(Transcription Factor CP2 (TFCP2))
Alternative Name
TFCP2
Background
TFCP2 binds a variety of cellular and viral promoters including fibrinogen, alpha-globin, SV40 and HIV-1 promoters. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1. It also functions as part of the SSP (stage selector protein) complex. TFCP2 facilitates the interaction of the gamma-globin genes with enhancer elements contained in the locus control region in fetal erythroid cells. It interacts by binding to the stage selector element (SSE) in the proximal gamma-globin promoter.Synonyms: Alpha-globin transcription factor CP2, LSF, SAA3 enhancer factor, SEF