Tropomyosin antibody

Catalog No. ABIN1109348

The Mouse Monoclonal anti-Tropomyosin antibody has been validated for WB, IF and IHC (fro). It is suitable to detect Tropomyosin in samples from Human, Rat, Mouse and Chicken.

Quick Overview for Tropomyosin antibody (ABIN1109348)

Target: Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))

Reactivity: Human, Rat, Mouse, Chicken

Host: Mouse

Clonality: Monoclonal

Conjugate: This Tropomyosin antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: TM-36

Product Details anti-Tropomyosin Antibody

Specificity: This antibody reacts to Tropomyosin-1 (TPM1).

Purification: Affinity chromatography

Immunogen: Chicken gizzard tropomyosin

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 1.2 % sodium acetate or neutral PBS

Concentration: 0,1 mg/mL

Buffer: 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Tropomyosin

Target: Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))

Alternative Name: Tropomyosin-1 (TPM1)

Background: The tropomyosins are a family of actin filament binding proteins. These proteins were first isolated from skeletal muscle, but later identified in many nonmuscle tissues. Tropomyosins are ubiquitous proteins of 35 to 45 kD associated with the actin filaments of myofibrils and stress fibers. Vertebrates have at least 4 different tropomyosin genes, in humans, they are named TPM1, TPM2, TPM3, and TPM4. Tropomyosins expressed as different isoforms in muscle and non-muscle cells.Synonyms: Alpha-tropomyosin, C15orf13, TMSA, Tropomyosin alpha-1 chain

Gene ID: 7168

NCBI Accession: NP_000357

UniProt: P09493

Pathways: Regulation of Actin Filament Polymerization