YWHAB antibody

Catalog No. ABIN1112791

This Mouse Monoclonal antibody specifically detects YWHAB in WB. It exhibits reactivity toward Mouse.

Quick Overview for YWHAB antibody (ABIN1112791)

Target: YWHAB (14-3-3 alpha + beta (YWHAB))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This YWHAB antibody is un-conjugated

Application: Western Blotting (WB)

Clone: N14

Product Details anti-YWHAB Antibody

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to the C-terminal of mouse 14-3-3 beta / alpha.

Isotype: IgG2a

Application Details

Application Notes: WB (1:1000-2000). Other applications have not been tested. The optimal dilutions should be determined by end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: TBS (pH7.4), 0.5% BSA, 25% Glycerol and 0.05% Sodium Azide.

Preservative: Sodium azide, Thimerosal (Merthiolate)

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C after thawing (1 week). Aliquot and store at -20 °C for long term (at least one year). Avoid repeated freeze and thaw cycles.

Expiry Date: 12 months

Target Details for YWHAB

Target: YWHAB (14-3-3 alpha + beta (YWHAB))

Alternative Name: 14-3-3 beta / alpha

Background: 14-3-3 proteins are a family of conserved regulatory molecules expressed in all eukaryotic cells. They have the ability to bind a multitude of functionally diverse signaling proteins, including kinases, phosphatases, and transmembrane receptors. More than 100 signaling proteins have been reported as 14-3-3 ligands, 14-3-3 b/a is one of them. They play important roles in a wide range of vital regulatory processes, such as mitogenic signal transduction, apoptotic cell death, and cell cycle control. Elevated amounts of 14-3-3 proteins are found in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease.

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, Maintenance of Protein Location