ACTC1 antibody

Catalog No. ABIN1112792

The Mouse Monoclonal anti-ACTC1 antibody has been validated for WB. It is suitable to detect ACTC1 in samples from Mouse and Rat.

Quick Overview for ACTC1 antibody (ABIN1112792)

Target: ACTC1 (Actin, Alpha, Cardiac Muscle 1 (ACTC1))

Reactivity: Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This ACTC1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: M8

Product Details anti-ACTC1 Antibody

Immunogen: A synthetic peptide (conjugated to KLH) corresponding to the N-terminal residues of alpha-Actin.

Isotype: IgG1

Application Details

Application Notes: WB (1:5000). Other applications have not been tested. The optimal dilutions should be determined by end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide.

Preservative: Sodium azide, Thimerosal (Merthiolate)

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C after thawing (1 week). Aliquot and store at -20 °C for long term (at least one year). Avoid repeated freeze and thaw cycles.

Expiry Date: 12 months

Target Details for ACTC1

Target: ACTC1 (Actin, Alpha, Cardiac Muscle 1 (ACTC1))

Background: Actin, alpha, skeletal muscle 1 (ACTA1) gene encodes skeletal muscle alpha-actin, which is the predominant actin isoform in the sarcomeric thin filaments of adult skeletal muscle, and essential, along with myosin, for muscle contraction. 1 Actin alpha 1 which is expressed in skeletal muscle is one of six different actin isoforms which have been identified. Actins are highly conserved proteins that are involved in cell motility, structure and integrity. Alpha actins are a major constituent of the contractile apparatus. 2 Alpha-skeletal actin can activate a regulatory pathway linking a subset of muscle genes that operates independently of normal differentiation and withdrawal from the cell cycle. 3

Pathways: Myometrial Relaxation and Contraction