Caveolin-1 antibody

Catalog No. ABIN1112799

This anti-Caveolin-1 antibody is a Mouse Monoclonal antibody detecting Caveolin-1 in WB. Suitable for Rat and Mouse.

Quick Overview for Caveolin-1 antibody (ABIN1112799)

Target: Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

Reactivity: Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Caveolin-1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: D16

Product Details anti-Caveolin-1 Antibody

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to the C-terminal of mouse Caveolin-1.

Isotype: IgG1

Application Details

Application Notes: WB (1:500-1000). Other applications have not been tested. The optimal dilutions should be determined by end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: TBS (pH7.4), 0.5% BSA, 25% Glycerol and 0.05% Sodium Azide.

Preservative: Sodium azide, Thimerosal (Merthiolate)

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C after thawing (1 week). Aliquot and store at -20 °C for long term (at least one year). Avoid repeated freeze and thaw cycles.

Expiry Date: 12 months

Target Details for Caveolin-1

Target: Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

Alternative Name: Caveolin-1

Background: Caveolins are a family of integral membrane proteins which are the principal components of caveolae membranes and involved in receptor-independent endocytosis. , they are found in the majority of adherent, mammalian cells, and played an important role during the development of atherosclerosis. Caveolin 1(CAV1) is a member of Caveolin gene family, and most prominently expressed in endothelial, fibrous and adipose tissue. It contains 3 exons spanning about 22 kD. It can link the integrin alpha subunit to the tyrosine kinase as a membrane adaptor .

Pathways: Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals