KRT17 antibody

Catalog No. ABIN1112805

This anti-KRT17 antibody is a Mouse Monoclonal antibody detecting KRT17 in WB. Suitable for Rat and Mouse.

Quick Overview for KRT17 antibody (ABIN1112805)

Target: KRT17 (Keratin 17 (KRT17))

Reactivity: Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This KRT17 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: C58

Product Details anti-KRT17 Antibody

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to the N-terminal of mouse CK17.

Isotype: IgG2a

Application Details

Application Notes: WB (1:2000). Other applications have not been tested. The optimal dilutions should be determined by end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: TBS (pH7.4), 0.5% BSA, 25% Glycerol and 0.05% Sodium Azide.

Preservative: Sodium azide, Thimerosal (Merthiolate)

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C after thawing (1 week). Aliquot and store at -20 °C for long term (at least one year). Avoid repeated freeze and thaw cycles.

Expiry Date: 12 months

Target Details for KRT17

Target: KRT17 (Keratin 17 (KRT17))

Alternative Name: Cytokeratin 17, CK17

Background: Cytokeratin 17, also known as Keratin, type I cytoskeletal 17 (K17) is a protein that in humans is encoded by the KRT17 gene. Keratin 17 (K17) is a differentiation-specific keratin expressed in the nail bed, hair follicle, sebaceous gland and other epidermal appendages. 1 The KRT17 gene is 5 kb long with 8 exons. Mutations in the gene encoding this protein lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex. Cytokeratin 17 synthesis seems to be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial stem cells. 2