Junctophilin 2 antibody

Catalog No. ABIN1112815

This Mouse Monoclonal antibody specifically detects Junctophilin 2 in WB and ICC. It exhibits reactivity toward Mouse and Rat.

Quick Overview for Junctophilin 2 antibody (ABIN1112815)

Target: Junctophilin 2 (JPH2)

Reactivity: Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This Junctophilin 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC)

Clone: D5-3

Product Details anti-Junctophilin 2 Antibody

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to the region of human JPH-2.

Isotype: IgG1

Application Details

Application Notes: WB (1:500-1000), ICC (1:50-100). Other applications have not been tested. The optimal dilutions should be determined by end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide.

Preservative: Sodium azide, Thimerosal (Merthiolate)

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C after thawing (1 week). Aliquot and store at -20 °C for long term (at least one year). Avoid repeated freeze and thaw cycles.

Expiry Date: 12 months

Target Details for Junctophilin 2

Target: Junctophilin 2 (JPH2)

Alternative Name: Junctophilin-2, JPH-2

Background: Junctophilin 2, also known as JPH2, is a member of the junctophilin gene family (the other members of the family are JPH1, JPH3, and JPH4), located between the plasma membrane (PM) and endoplasmic/sarcoplasmic reticulum (ER/SR). It is the predominant isoform in cardiac tissue, and also expressed with JPH1 in skeletal muscle. JPH2 has been shown to be downregulated in several animal models of heart failure.