LTA antibody

Catalog No. ABIN1112819

Product Details anti-LTA Antibody

Target: LTA (Lymphotoxin-alpha (LTA))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This LTA antibody is un-conjugated

Application: Western Blotting (WB)

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to the region of human LT-alpha.

Clone: M42-5

Isotype: IgG1

Application Details

Application Notes: WB (1:500). Other applications have not been tested. The optimal dilutions should be determined by end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide.

Preservative: Sodium azide, Thimerosal (Merthiolate)

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C after thawing (1 week). Aliquot and store at -20 °C for long term (at least one year). Avoid repeated freeze and thaw cycles.

Expiry Date: 12 months

Target Details for LTA

Target: LTA (Lymphotoxin-alpha (LTA))

Abstract: LTA Products

Target Type: Chemical

Background: Lymphotoxin-alpha, a member of the tumor necrosis factor family , is a cytokine produced by lymphocytes. It is a glycoprotein with a relative molecular mass (Mr) of 60,000-70,000. LTA is highly inducible, secreted, and exists as homotrimeric molecule. It forms heterotrimers with lymphotoxin-beta which anchors lymphotoxin-alpha to the cell surface. LTA mediates a large variety of inflammatory, immunostimulatory, and antiviral responses. It is also involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis.

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process