DCHS1
Reactivity: Human
WB, ICC
Host: Rabbit
Polyclonal
unconjugated
Application Notes
WB (1:500-1000), ICC (1:50-100). Other applications have not been tested. The optimal dilutions should be determined by end user.
Restrictions
For Research Use only
Format
Liquid
Buffer
TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide.
Preservative
Sodium azide, Thimerosal (Merthiolate)
Storage
4 °C/-20 °C
Storage Comment
Store at 4 °C after thawing (1 week). Aliquot and store at -20 °C for long term (at least one year). Avoid repeated freeze and thaw cycles.
Expiry Date
12 months
Target
DCHS1
(Dachsous 1 (DCHS1))
Alternative Name
Protocadherin-16
Background
Protocadherin-16 (PCDH16), as known as Protein dachsous homolog 1 or cadherin-19 (CDH19) or cadherin-25 (CDH25) or fibroblast cadherin-1 (FIB1), is a protein that in humans is encoded by the DCHS1 gene. This gene is a member of the cadherin superfamily whose members encode calcium-dependent cell-cell adhesion molecules. The encoded protein has a signal peptide, 27 cadherin repeat domains and a unique cytoplasmic region. This particular cadherin family member is expressed in fibroblasts but not in melanocytes or keratinocytes. The cell-cell adhesion of fibroblasts is thought to be necessary for wound healing.