Factor XI antibody

Catalog No. ABIN111407

The Mouse Monoclonal anti-Factor XI antibody has been validated for WB, RIA, EIA and Func. It is suitable to detect Factor XI in samples from Human.

Quick Overview for Factor XI antibody (ABIN111407)

Target: Factor XI (F11) (Coagulation Factor XI (F11))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Factor XI antibody is un-conjugated

Application: Western Blotting (WB), Radioimmunoassay (RIA), Enzyme Immunoassay (EIA), Functional Studies (Func)

Clone: HfXI-2

Product Details anti-Factor XI Antibody

Specificity: Reacts with human Factor XI.

Purification: Ammonium sulfate precipitation, ion exchange chromatography and gel filtration

Immunogen: Human Factor XI

Isotype: IgG

Application Details

Application Notes: Inhibitory in clotting assays. Useful for purification of Factor XI. Western blot (non-reduced samples only, band size 160 kD). RIA. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 12.4 mg/mL (OD280 nm, E1% = 14)

Buffer: 50 % (vol/vol) glycerol/water) without preservatives

Preservative: Without preservative

Handling Advice: This product is photosensitive and should be protected from light

Storage: 4 °C

Storage Comment: Store the antibody at 2 - 8 °C. DO NOT FREEZE!

Target Details for Factor XI

Target: Factor XI (F11) (Coagulation Factor XI (F11))

Background: Factor X is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a haemorrhagic condition of variable severity.Synonyms: FX1, PTA, Plasma thromboplastin antecedent

Gene ID: 2160

NCBI Accession: NP_000119

UniProt: P03951