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KRT15 antibody (C-Term)

This anti-KRT15 antibody is a Mouse Monoclonal antibody detecting KRT15 in IF and IHC (p). Suitable for Human, Rat, Mouse and Cow.
Catalog No. ABIN114888

Quick Overview for KRT15 antibody (C-Term) (ABIN114888)

Target

See all KRT15 Antibodies
KRT15 (Keratin 15 (KRT15))

Reactivity

  • 154
  • 47
  • 27
  • 26
  • 2
Human, Rat, Mouse, Cow

Host

  • 88
  • 71
  • 2
Mouse

Clonality

  • 95
  • 66
Monoclonal

Conjugate

  • 63
  • 19
  • 7
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This KRT15 antibody is un-conjugated

Application

  • 92
  • 91
  • 63
  • 52
  • 42
  • 19
  • 16
  • 14
  • 14
  • 14
  • 14
  • 10
  • 6
  • 5
  • 2
  • 1
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

LHK15
  • Binding Specificity

    • 18
    • 15
    • 7
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Specificity

    Cytokeratin 15 is a type I cytokeratin without a defined type II partner.
    Cellular Localization: Cytoplasmic.

    Purification

    Purified

    Immunogen

    A 17-mer synthetic peptide from the C-terminus of human cytokeratin 15

    Isotype

    IgG2a
  • Application Notes

    Immunoflourescence. Immunohistochemistry on Paraffin Embedded Sections: 1/25-1/75 dilution in an ABCmethod (30 minutes at room temperature). Requires high temperature antigen unmaskingwith 10 mM citrate buffer, pH 6.0 prior to immunostaining. Recommended Positive Control: Skin.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Handling Advice

    Avoid repeated freezing and thawing.

    Storage

    4 °C/-20 °C

    Storage Comment

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target

    KRT15 (Keratin 15 (KRT15))

    Alternative Name

    Cytokeratin 15

    Background

    Cytokeratin 15 is expressed primarily in the basal keratinocytes of stratified tissues, including the fetal epidermis and fetal nail. A number of human cytokeratins are expressed during the development of stratified epithelia from one-layered polar epithelia and continue to be expressed in several adult epithelial tissues. Cytokeratin 15 (CK15) is a type I keratin without a defined type II partner whose expression in epidermal diseases has not been investigated. A monoclonal antibody raised against the last 17 amino acids of the CK15 polypeptide show that CK-15 is expressed primarily in the basal keratinocytes of stratified tissues, including the fetal epidermis and fetal nail. Although CK-15 in normal hair follicles was virtually absent from hair bulbs, it was expressed by a subset of keratinocytes in the outer root sheath. In human conjunctival epithelium, strong expression of CK-15 was observed in basal cells, whereas CK19 was expressed in both basal and suprabasal layers. Although the expression of K15 and K19 differ in humans and mice, specific staining patterns can be used to characterize the epithelial phenotype in normal and diseased ocular surface.Synonyms: CK-15, Cytokeratin-15, K15, KRT15, KRTB, Keratin, Keratin 15, Keratin-15, Type I Cytoskeletal 15

    Gene ID

    3866

    NCBI Accession

    NP_002266

    UniProt

    P19012
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