Stearoyl-Coenzyme A Desaturase 1 (SCD1) (AA 21-33) antibody

Catalog No. ABIN1169094

This anti- antibody is a Rabbit Polyclonal antibody detecting in WB and ELISA. Suitable for Mouse.

Quick Overview for Stearoyl-Coenzyme A Desaturase 1 (SCD1) (AA 21-33) antibody (ABIN1169094)

Target: Stearoyl-Coenzyme A Desaturase 1 (SCD1)

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA

Product Details

Binding Specificity: AA 21-33

Specificity: Recognizes mouse SCD1. Detects a band of ~41 kDa by Western Blot.

Cross-Reactivity: Mouse (Murine)

Sterility: 0.2 μm filtered

Immunogen: Synthetic peptide corresponding to aa 21-33 (A21PPSGNEREKVKT33) of mouse SCD1.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C.

Expiry Date: 6 months

Target Details

Target: Stearoyl-Coenzyme A Desaturase 1 (SCD1)

Alternative Name: Stearoyl-CoA Desaturase-1

Background: Stearoyl-CoA desaturase (SCD) is a regulatory enzyme in lipogenesis. The enzyme is constitutively expressed in adipose tissue and is induced in liver in response to fat free, high carbohydrate diet. Several SCD isoforms (SCD1, -2, and -3) exist in the mouse. Mice with a targeted disruption of the SCD1 isoform had reduced body adiposity, increased insulin sensitivity, and resistance to diet-induced weight gain. The protection from obesity involved increased energy expenditure and increased oxygen consumption. SCD1 deficiency shows activation of lipid oxidation in addition to reduced triglyceride synthesis and storage.

UniProt: P13516

Pathways: Brown Fat Cell Differentiation