Adiponectin Receptor 1 antibody (AA 2-36)

Catalog No. ABIN1169254

Product Details anti-Adiponectin Receptor 1 Antibody

Target: Adiponectin Receptor 1 (ADIPOR1)

Binding Specificity: AA 2-36

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Adiponectin Receptor 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: Recognizes human adiponectin receptor 1.

Cross-Reactivity: Human

Immunogen: Synthetic peptide corresponding to aa 2-36 (S2SHKGSVVAQGNGAPASNREADTVELAEL GPLLEE36) of human adiponectin receptor 1.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Neat serum containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Expiry Date: 12 months

References for anti-Adiponectin Receptor 1 antibody (ABIN1169254)

Corbetta, Redaelli, Pozzi, Bovo, Ratti, Redaelli, Pellegrini, Beck-Peccoz, Spada: "Fibrosis is associated with adiponectin resistance in chronic hepatitis C virus infection." in: European journal of clinical investigation, Vol. 41, Issue 8, pp. 898-905, (2011) (PubMed).

Target Details for Adiponectin Receptor 1

Target: Adiponectin Receptor 1 (ADIPOR1)

Alternative Name: Adiponectin Receptor 1 (ADIPOR1 Products)

Background: AdipoR1 is a receptor for globular and full-length adiponectin, an essential hormone secreted by adipocytes that acts as an antidiabetic. AdipoR1 is probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. It mediates increased AMPK, PPAR-alpha ligand activity, fatty acid oxidation and glucose uptake by adiponectin. It is a high-affinity receptor for globular adiponectin but low-affinity receptor for full-length adiponectin. It is widely expressed.

UniProt: Q96A54

Pathways: AMPK Signaling