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DDX58 antibody (AA 201-713) (Biotin)

DDX58 Reactivity: Human, Mouse WB, IHC, IP Host: Mouse Monoclonal Alme-1 Biotin

Catalog No. ABIN1169335

Datasheet as PDF

Target See all DDX58 Antibodies

DDX58 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))
Binding Specificity
15

5

5

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 201-713
Reactivity
68

39

16

2

1
Human, Mouse
Host
64

7

1
Mouse
Compatible Secondaries
Clonality
66

6
Monoclonal
Conjugate
34

4

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1
This DDX58 antibody is conjugated to Biotin
Application
59

20

14

14

13

11

6

5

4

3

3

2

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Specificity

Recognizes human and mouse RIG-I.

Cross-Reactivity

Human, Mouse (Murine)

Purification

Purified from concentrated hybridoma tissue culture supernatant.

Purity

>95 % (SDS-PAGE)

Immunogen

Recombinant human RIG-I (aa 201-713).

Clone

Alme-1

Isotype

IgG1

Top Product

Discover our top product DDX58 Primary Antibody
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) (AA 550-776) antibody
DDX58 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) (AA 1-211) antibody
DDX58 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) (C-Term) antibody
Verified DDX58 Reactivity: Human ELISA, IHC, IF, FACS Host: Goat Polyclonal unconjugated

anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) (AA 789-925) antibody
DDX58 Reactivity: Human ELISA, ICC, FACS Host: Mouse Monoclonal 4G1B6 unconjugated

anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) antibody
DDX58 Reactivity: Human WB, IHC, IF, IHC (p) Host: Mouse Monoclonal 6C1 unconjugated

anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) (C-Term) antibody
DDX58 Reactivity: Human WB, IHC, IP, IF Host: Rabbit Polyclonal unconjugated

anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) (AA 894-925), (C-Term) antibody
DDX58 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal RB8008 unconjugated

anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) (AA 726-925) antibody
DDX58 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated

anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) (N-Term) antibody
DDX58 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated

anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) (AA 200-250) antibody
DDX58 Reactivity: Human, Monkey WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated

Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Format

Liquid

Concentration

Lot specific

Buffer

In PBS containing 0.02 % sodium azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Expiry Date

12 months
Target

DDX58 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))

Alternative Name

RIG-I (DDX58 Products)

Background

RIG-I and MDA5 are highly conserved helicases involved in the innate immune response to virus. RIG-I is a member of the DEAD-box RNA helicases and is activated by cytoplasmic dsRNA and 5'-ppp RNA produced during the viral replication. The protein is characterized by a N-terminal region with two caspase recruitment domains (CARD) and a C-terminal region harboring potential ATP-dependent RNA helicase activity. RIG-I recruits the CARD adaptor inducing IFN-beta (Cardif) in a CARD-CARD-dependent manner resulting in NF-kappaB and IRF3 activation.

UniProt

O95786

Pathways

Activation of Innate immune Response, Hepatitis C