CD16 antibody (Biotin)

Catalog No. ABIN118539

This anti-CD16 antibody is a Mouse Monoclonal antibody detecting CD16 in FACS. Suitable for Human.

Quick Overview for CD16 antibody (Biotin) (ABIN118539)

Target: CD16

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD16 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS)

Clone: LNK16

Product Details anti-CD16 Antibody (Biotin)

Specificity: This antibody recognises CD16.

Purification: Ion Exchange Chromatography

Immunogen: Normal human peripheral blood granulocytes. Spleen cells from immunised BALB/c mice were fused with cells of the mouse X63.653 myeloma cell line.

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry: Neat-1/5, Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL human whole blood.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % Bovine Serum Albumin as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CD16

Target: CD16

Alternative Name: CD16

Background: CD16 is a 50-65kD cell surface molecule which exists in two forms - a transmembranous form expressed by NK cells and some T cells, and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC by NK cells.Synonyms: CD16A, FCG3, FCGR3, FCGR3A, Fc-gamma RIII, Fc-gamma RIII-alpha, Fc-gamma RIIIa, FcR-10, FcRIII, FcRIIIa, IGFR3, IgG Fc receptor III-2, Low affinity immunoglobulin gamma Fc region receptor III-A

Gene ID: 2214

NCBI Accession: NP_000560

UniProt: P08637

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process