TNNI3 antibody

Catalog No. ABIN118970

The Mouse Monoclonal anti-TNNI3 antibody has been validated for WB and EIA. It is suitable to detect TNNI3 in samples from Human, Rat, Pig, Dog, Cow, Rabbit, Goat and Cat.

Quick Overview for TNNI3 antibody (ABIN118970)

Target: TNNI3 (Cardiac Troponin I (TNNI3))

Reactivity: Human, Rat, Pig, Dog, Cow, Rabbit, Goat, Cat

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNNI3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: 110 (10F4)

Product Details anti-TNNI3 Antibody

Specificity: This antibody is specific for amino acids 34-37 of Troponin I from Human heart. There is no cross-reactivity with skeletal muscle Troponin I.

Purification: Affinity Chromatography on Protein A.

Immunogen: Purified human Cardiac Troponin I.

Isotype: IgG2a

Application Details

Application Notes: Suitable for ELISA and Western blotting.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS pH 7.4, containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for TNNI3

Target: TNNI3 (Cardiac Troponin I (TNNI3))

Alternative Name: Cardiac Troponin I

Background: Troponin I is part of a heteromeric complex playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI), troponin T (TnT) and troponin C (TnC). Each subunit is responsible for part of troponin complex function. E.g. TnI inhibits ATP-ase activity of acto-myosin. TnT and TnI are presented in cardiac muscles in different forms than in skeletal muscles. Only one tissue-specific isoform of TnI is described for cardiac muscle tissue (cTnI). cTnI is expressed only in myocardiumSynonyms: TNNC1, TNNI3

Gene ID: 7137

NCBI Accession: NP_000354

UniProt: P19429