IGF2R antibody

Catalog No. ABIN119770

This Mouse Monoclonal antibody specifically detects IGF2R in FACS. It exhibits reactivity toward Human.

Quick Overview for IGF2R antibody (ABIN119770)

Target: IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IGF2R antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: MEM-238

Product Details anti-IGF2R Antibody

Specificity: This antibody recognises CD222. Clone MEM-238 recognises an epitope located in the region between extracellular domains 2 and 5 (aa 192-697) of CD222. CD222 is primarily expressed intracellularly with a small percentage of molecules being located at the cell surface (5 - 10 %).

Purification: Affinity chromatography on Protein G

Isotype: IgG1

Application Details

Application Notes: Flow cytometry: 1/25 - 1/50, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for IGF2R

Target: IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))

Alternative Name: CD222 / IGF2R

Background: CD222 is a 250 KD transmembrane protein originally identified as the IGF II receptor. CD222 is ubiquitously expressed and is involved with internalization of a variety of ligands.Synonyms: 300 kDa mannose 6-phosphate receptor, CI Man-6-P receptor, CI-MPR, Insulin-like growth factor 2 receptor, Insulin-like growth factor II receptor, Late Endosome Marker, M6P/IGF2 receptor, M6P/IGF2R, M6PR, MPR 300, Mannose 6 Phosphate Receptor (Cation independent)

Gene ID: 3482

NCBI Accession: NP_000867

UniProt: P11717