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IL-2 antibody (PE)

IL2 Reactivity: Human, Monkey FACS Host: Rat Monoclonal MQ1-17H12 PE

Catalog No. ABIN119948

Datasheet as PDF

Target See all IL-2 (IL2) Antibodies

IL-2 (IL2) (Interleukin 2 (IL2))
Reactivity
139

82

42

13

9

7

6

6

5

4

4

3

3

2

1

1

1

1
Human, Monkey
Host
115

80

55

10

4

2

1
Rat
Compatible Secondaries
Clonality
138

126

1
Monoclonal
Conjugate
144

36

24

19

16

9

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This IL-2 antibody is conjugated to PE
Application
159

127

64

59

40

28

24

21

14

14

13

13

12

11

10

8

6

6

4

4

3

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1
Flow Cytometry (FACS)

Clone

MQ1-17H12

Isotype

IgG2a

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anti-Interleukin 2 (IL2) (AA 21-153) antibody
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anti-Interleukin 2 (IL2) (AA 10-169) antibody
IL2 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Interleukin 2 (IL2) (AA 21-153) antibody
IL2 Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal C5 unconjugated

anti-Interleukin 2 (IL2) antibody
IL2 Reactivity: Human WB, ELISA, FACS, IP, ICC Host: Mouse Monoclonal 35C3 unconjugated

anti-Interleukin 2 (IL2) antibody (APC)
IL2 Reactivity: Human FACS Host: Mouse Monoclonal 35C3 APC

anti-Interleukin 2 (IL2) antibody (PE)
IL2 Reactivity: Human FACS Host: Mouse Monoclonal 35C3 PE

anti-Interleukin 2 (IL2) (AA 21-153) antibody
IL2 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated

anti-Interleukin 2 (IL2) antibody
IL2 Reactivity: Human WB, ELISA, FACS Host: Rabbit Monoclonal unconjugated

anti-Interleukin 2 (IL2) (AA 21-155) antibody
IL2 Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

Application Notes

Flow Cytometry: Neat - 1/10, Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood,Membrane permeabilisation is required for this application.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions

For Research Use only
Buffer

PBS containing 0.09 % Sodium Azide and 0.5 % Bovine Serum Albumin

Preservative

Sodium azide

Precaution of Use

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice

Dilute only prior to immediate use

Storage

4 °C

Storage Comment

Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! Freezing alkaline phosphatase conjugates will result in a substantial loss of enzymatic activity.
Target

IL-2 (IL2) (Interleukin 2 (IL2))

Alternative Name

Interleukin-2 / IL2 (IL2 Products)

Background

Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells.Synonyms: IL-2, T-cell growth factor, TCGF

Gene ID

9606

UniProt

P60568

Pathways

JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation