KIR2DL4/CD158d antibody
Quick Overview for KIR2DL4/CD158d antibody (ABIN1302514)
Target
See all KIR2DL4/CD158d (KIR2DL4) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- Anti-Hu CD158d Purified Low Endotoxin
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Specificity
- The mouse monoclonal antibody mAb#33 (also known as mAb 33 or 33) recognizes extracellular portion of CD158d / KIR2DL4, a 45 kDa NK cell marker. Cell surface expression and function of CD158d / KIR2DL4 depends on genotype of particular individuals.
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Purification
- Purified by protein-A affinity chromatography.
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Endotoxin Level
- Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
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Immunogen
- NK3.3 cells and KIR2DL4-Ig fusion protein
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Isotype
- IgG1 kappa
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anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 4 (KIR2DL4) antibody
KIR2DL4 Reactivity: Human FACS, IP, ICC Host: Mouse Monoclonal mAb 33 unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 4 (KIR2DL4) (AA 296-323), (C-Term) antibodyKIR2DL4 Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB23034 unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 4 (KIR2DL4) (AA 22-120) antibodyKIR2DL4 Reactivity: Human FACS, ELISA Host: Mouse Monoclonal 2E3E12 unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 4 (KIR2DL4) antibody (APC)KIR2DL4 Reactivity: Human FACS Host: Mouse Monoclonal mAb 33 APC
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 4 (KIR2DL4) (Center) antibodyKIR2DL4 Reactivity: Human WB, IHC (p), ICC, IF Host: Rabbit Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 4 (KIR2DL4) antibody (PE)KIR2DL4 Reactivity: Human FACS Host: Mouse Monoclonal mAb 33 PE
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 4 (KIR2DL4) (AA 1-377) antibodyKIR2DL4 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 4 (KIR2DL4) (AA 302-332), (C-Term) antibodyKIR2DL4 Reactivity: Human WB, FACS, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 4 (KIR2DL4) (AA 22-242) antibodyKIR2DL4 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 4 (KIR2DL4) (AA 51-150) antibodyKIR2DL4 Reactivity: Human WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
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Application Notes
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Flow cytometry: Recommended dilution: 2-6 μg/mL.
Functional application: Activation. -
Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4
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Storage
- 4 °C
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Storage Comment
- Store at 2-8°C. Do not freeze.
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- KIR2DL4/CD158d (KIR2DL4) (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 4 (KIR2DL4))
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Alternative Name
- CD158d
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Background
- Killer cell immunoglobulin like receptor, two Ig d,CD158d / KIR2DL4 is a KIR family member that shares structural features with both activating and inhibitory receptors and may mediate different functions under different circumstances. It contains cytoplasmic ITIM, suggesting inhibitory function, but also transmembrane domain similar to those of activating KIRs. It has been reported that CD158d serves as an inhibitory receptor for peripheral and uterine NK cells, but its ligation with soluble mAbs (unlike immobilized mAbs) results in activation of IFN-γ, secretion. CD158d also binds both membrane form and soluble form of its ligand HLA-G.,KIR2DL4, KIR103AS, 103AS, 15.212
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Gene ID
- 3805
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UniProt
- Q99706
Target
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