MPHOSPH8 antibody (AA 50-120)

Catalog No. ABIN1304834

Product Details anti-MPHOSPH8 Antibody

Target: MPHOSPH8 (M-Phase phosphoprotein 8 (MPHOSPH8))

Binding Specificity: AA 50-120

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MPHOSPH8 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC)

Specificity: No off-targets reported

Cross-Reactivity: Human

Characteristics:

Description: Our Anti-MPP8 mouse monoclonal primary antibody is produced in-house from hybridoma clone N119/44. It detects human MPP8, and is purified by Protein A chromatography. It is great for use in ICC, WB.

Manufacturer Comment: We produce our MPP8 mouse monoclonal primary antibody from hybridoma clone N119/44. It is great in ICC, WB and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.

Purity: > 90% specific antibody

Immunogen: Fusion protein amino acids 50-120 (Chromo domain) of human MPP8 (accession number Q99549) produced recombinantly in E. Coli

Clone: N119-44

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Expiry Date: 24 months

Target Details for MPHOSPH8

Target: MPHOSPH8 (M-Phase phosphoprotein 8 (MPHOSPH8))

Alternative Name: MPP8 (MPHOSPH8 Products)

Background:

Synonyms: M-phase phosphoprotein 8 (Two hybrid-associated protein 3 with RanBPM) (Twa3)

Target Description: M-Phase Phosphoprotein 8 is encoded by the gene MPHOSPH8. MPHOSPH8 is a heterochromatin component that specifically recognizes and binds methylated 'Lys-9' of histone H3 (H3K9me) and promotes recruitment of proteins that mediate epigenetic repression. MPHOSPH8 is expressed in the brain. Diseases associated with MPHOSPH8 include Charcot-Marie-Tooth Disease.

Gene Name Alternatives: MPHOSPH8 MPP8

Molecular Weight: 100 kDa

NCBI Accession: NP_059990