Neuroligin 3 antibody (AA 730-848)

Catalog No. ABIN1304859

This anti-Neuroligin 3 antibody is a Mouse Monoclonal antibody detecting Neuroligin 3 in WB, IHC and ICC. Suitable for Rat.

Quick Overview for Neuroligin 3 antibody (AA 730-848) (ABIN1304859)

Target: Neuroligin 3 (NLGN3)

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This Neuroligin 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: N110-29

Product Details anti-Neuroligin 3 Antibody

Binding Specificity: AA 730-848

Specificity: No off-targets reported for Neuroligin-1, -2, -4 or -4*

Cross-Reactivity: Human, Mouse, Rat

Characteristics:

Description: Our Anti-Neuroligin-3 mouse monoclonal primary antibody is produced in-house from hybridoma clone N110/29. It is KO validated, detects human and mouse Neuroligin-3, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Manufacturer Comment: We produce our Neuroligin-3 mouse monoclonal primary antibody from hybridoma clone N110/29. It is great in IHC, ICC, WB and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.

Purity: > 90% specific antibody

Immunogen: Fusion protein amino acids 730-848 (intracellular C-terminus) of rat Neuroligin-3 (accession number AAA97871) produced recombinantly in E. Coli

Isotype: IgG1

Application Details

Application Notes:

Dilution Range: ICC: 1:300

Dilution Range: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Expiry Date: 24 months

Target Details for Neuroligin 3

Target: Neuroligin 3 (NLGN3)

Alternative Name: Neuroligin-3

Background:

Synonyms: Neuroligin-3 (Gliotactin homolog)

Target Description: Neuroligin3 is encoded by the gene NLGN3. Neuroligin3 is a transmembrane scaffolding protein and cell adhesion molecule. It is involved in cell-cell interactions in neurons and in other cell types. It is expressed in many tissues, including the brain where it is located at the postysynaptic membrane and is involved in regulation of excitatory synapses, synapse formation and synaptic transmission. Mutations in this gene may be associated with autism and Asperger syndrome.

Gene Name Alternatives: Nlgn3

Molecular Weight: 110 kDa

Pathways: Synaptic Membrane