LRRC4B antibody (AA 598-709)

Catalog No. ABIN1304869

This Mouse Monoclonal antibody specifically detects LRRC4B in WB, IHC, ICC and IP. It exhibits reactivity toward Rat.

Quick Overview for LRRC4B antibody (AA 598-709) (ABIN1304869)

Target: LRRC4B (Leucine Rich Repeat Containing 4B (LRRC4B))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This LRRC4B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Clone: N51-6

Product Details anti-LRRC4B Antibody

Binding Specificity: AA 598-709

Specificity: No off-targets reported for NGL-1 or NGL-2

Cross-Reactivity: Mouse, Rat

Characteristics:

Description: Our Anti-NGL-3/LRRC4B mouse monoclonal primary antibody is produced in-house from hybridoma clone N51/6. It detects mouse and rat NGL-3/LRRC4B, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.

Manufacturer Comment: We produce our NGL-3/LRRC4B mouse monoclonal primary antibody from hybridoma clone N51/6. It is great in IHC, ICC, IP, WB and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.

Purity: > 90% specific antibody

Immunogen: Fusion protein amino acids 598-709 of rat NGL-3 (Leucine-rich repeat-containing 4B protein (Lrrc4B), accession number XP_218615) produced recombinantly in E. Coli

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Expiry Date: 24 months

Target Details for LRRC4B

Target: LRRC4B (Leucine Rich Repeat Containing 4B (LRRC4B))

Alternative Name: LRRC4B

Background:

Synonyms: Leucine-rich repeat-containing protein 4B (Netrin-G3 ligand) (NGL-3)

Target Description: Leucine Rich Repeat Containing 4B is encoded by the gene LRRC4B. LRRC4B is a synaptic adhesion protein that regulates the formation of excitatory synapses. The trans-synaptic adhesion between LRRC4B and PTPRF regulates the formation of excitatory synapses in a bidirectional manner. LRRC4B is expressed in the brain. No disorders were found to be associated with LRRC4B.

Gene Name Alternatives: Lrrc4b Lrig4

Molecular Weight: 100 kDa

UniProt: P0CC10

Pathways: Synaptic Membrane