CD86 antibody

Catalog No. ABIN1383878

The Mouse Monoclonal anti-CD86 antibody has been validated for FACS, ELISA and Func. It is suitable to detect CD86 in samples from Human. There are 3+ publications available.

Quick Overview for CD86 antibody (ABIN1383878)

Target: CD86

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD86 antibody is un-conjugated

Application: Flow Cytometry (FACS), ELISA, Functional Studies (Func)

Clone: B-T7

Product Details anti-CD86 Antibody

Specificity: Recognises the B7.2, B70 antigen, a 80 kDa protein

Purification: Ion exchange chromatography

Sterility: 0.22 μm filtered

Immunogen: B70 transfected P815 cell line,Myeloma X63/AG.8653 x Balb/c spleen cells

Isotype: IgG1 kappa

Biological Activity Comment: Inhibits mixed lymphocyte culture

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

Preservative: Without preservative

Storage: 4 °C

Storage Comment: Stable at +2-8°C for 12 months. For longer storage freeze aliquots.

References for anti-CD86 antibody (ABIN1383878)

Puig-Kröger, Relloso, Fernández-Capetillo, Zubiaga, Silva, Bernabéu, Corbí: "Extracellular signal-regulated protein kinase signaling pathway negatively regulates the phenotypic and functional maturation of monocyte-derived human dendritic cells." in: Blood, Vol. 98, Issue 7, pp. 2175-82, (2001) (PubMed).

Pellat-Deceunynck, Jego, Harousseau, Vié, Bataille: "Isolation of human lymphocyte antigens class I-restricted cytotoxic T lymphocytes against autologous myeloma cells." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 5, Issue 3, pp. 705-9, (1999) (PubMed).

Krzysiek, Lefèvre, Legendre, Treton, Dormont, Galanaud, Gras, Richard: "B cell-driven HIV type 1 expression in T cells: an essential role of CD86 costimulatory molecule." in: AIDS research and human retroviruses, Vol. 14, Issue 11, pp. 989-97, (1998) (PubMed).

Target Details for CD86

Target: CD86

Alternative Name: CD86

Background: B7-2

Molecular Weight: 80 kDa

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation