ANKRD20A1 antibody

Catalog No. ABIN1385482

This Rabbit Polyclonal antibody specifically detects ANKRD20A1 in WB, IF (p) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for ANKRD20A1 antibody (ABIN1385482)

Target: ANKRD20A1 (Ankyrin Repeat Domain 20 Family, Member A1 (ANKRD20A1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANKRD20A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ANKRD20A1 Antibody

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ANKRD20A1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for ANKRD20A1

Target: ANKRD20A1 (Ankyrin Repeat Domain 20 Family, Member A1 (ANKRD20A1))

Alternative Name: ANKRD20A1

Background:

Synonyms: A20A1_HUMAN, ANKRD20A, ANKRD20A1, Ankyrin repeat domain 20 family member A1, Ankyrin repeat domain 20A, Ankyrin repeat domain containing protein 20A1, Ankyrin repeat domain-containing protein 20A1, DKFZp434A171.

Background: Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD20A (ankyrin repeat domain-containing protein 20A) is an 823 amino acid protein that contains five ANK repeats. The gene encoding ANKRD20A maps to chromosome 9, which consists of about 145 million bases and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and familial dysautonomia are associated with chromosome 9. Also, chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.

Gene ID: 84210