STAU1/Staufen antibody

Catalog No. ABIN1385730

This anti-STAU1/Staufen antibody is a Rabbit Polyclonal antibody detecting STAU1/Staufen in WB, IF (cc), IF (p) and IHC (p). Suitable for Human, Rat and Mouse. This Primary Antibody has been cited in 1 publication.

Quick Overview for STAU1/Staufen antibody (ABIN1385730)

Target: STAU1/Staufen (STAU1) (Staufen Double-Stranded RNA Binding Protein 1 (STAU1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STAU1/Staufen antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-STAU1/Staufen Antibody

Cross-Reactivity: Chicken, Horse, Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Staufen

Isotype: IgG

Application Details

Application Notes: WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-STAU1/Staufen antibody (ABIN1385730)

de Morrée, van Velthoven, Gan, Salvi, Klein, Akimenko, Quarta, Biressi, Rando: "Staufen1 inhibits MyoD translation to actively maintain muscle stem cell quiescence." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 43, pp. E8996-E9005, (2017) (PubMed).

Target Details for STAU1/Staufen

Target: STAU1/Staufen (STAU1) (Staufen Double-Stranded RNA Binding Protein 1 (STAU1))

Background:

Synonyms: STAU, PPP1R150, Double-stranded RNA-binding protein Staufen homolog 1, STAU1

Background: Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site.

Gene ID: 6780

UniProt: O95793

Pathways: Asymmetric Protein Localization