C1QBP antibody (AA 101-200)

Catalog No. ABIN1386484

This Rabbit Polyclonal antibody specifically detects C1QBP in WB, ICC, ELISA, IF (cc), IF (p), IHC (p) and IHC (fro). It exhibits reactivity toward Mouse.

Quick Overview for C1QBP antibody (AA 101-200) (ABIN1386484)

Target: C1QBP (Complement Component 1, Q Subcomponent Binding Protein (C1QBP))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C1QBP antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-C1QBP Antibody

Binding Specificity: AA 101-200

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Sheep,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C1QBP

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for C1QBP

Target: C1QBP (Complement Component 1, Q Subcomponent Binding Protein (C1QBP))

Alternative Name: C1QBP/GC1q R

Background:

Synonyms: C1q globular domain binding protein, C1QBP, C1QBP_HUMAN antibody Complement component 1 q subcomponent binding protein, Complement component 1 Q subcomponent binding protein mitochondrial, Complement component 1 Q subcomponent-binding protein, mitochondrial, GC1Q R, GC1q R protein, GC1q-R protein, GC1QBP, GC1QR, Glycoprotein gC1qBP, HABP 1, HABP1, Hyaluronan binding protein 1, Hyaluronan-binding protein 1, Mitochondrial matrix protein p32, p32 antibody p33 antibody Pre mrna splicing factor SF2 P32 subunit precursor, SF2p32, Splicing factor SF2 associated protein.

Background: The human complement subcomponent C1q associates with C1r and C1s in order to yield the first component of the serum complement system (SCS). The SCS contains over 30 glycoproteins that influence physiological mechanisms of the body in response to immune complex (the classical pathway), carbohydrate (the lectin pathway) or bacterial (alternative pathway) initiation. C1q binding protein (C1QBP), also designated gC1q-R, p32 (p33) or HABP1 (hyaluronan-binding protein 1), is known to bind the globular heads of C1q molecules and inhibit C1 activation. C1QBP has been described as a complement receptor for C1q on B cells, neutrophils and mast cells. The C1QBP protein may form homodimers. C1QBP is expressed in vascular endothelial cells and has been found to be a multifunctional protein interacting with elements of complement, coagulation and kinin systems. In addition, C1QBP is a subunit of pre-mRNA splicing factor SF2/ASF.

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly