CPEB3 antibody (AA 251-350)

Catalog No. ABIN1386521

The Rabbit Polyclonal anti-CPEB3 antibody has been validated for WB, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) and ICC. It is suitable to detect CPEB3 in samples from Human.

Quick Overview for CPEB3 antibody (AA 251-350) (ABIN1386521)

Target: CPEB3 (Cytoplasmic Polyadenylation Element Binding Protein 3 (CPEB3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPEB3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Product Details anti-CPEB3 Antibody

Binding Specificity: AA 251-350

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CPEB3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CPEB3

Target: CPEB3 (Cytoplasmic Polyadenylation Element Binding Protein 3 (CPEB3))

Alternative Name: CPEB3

Background:

Synonyms: CPE-binding protein 3, CPE-BP3, CPEB 3, Cpeb3, CPEB3_HUMAN, Cytoplasmic polyadenylation element binding protein 3, Cytoplasmic polyadenylation element-binding protein 3, hCPEB-3, KIAA0940.

Background: The regulated translation of messenger RNA is essential for cell-cycle progression, establishment of the body plan during early development and modulation of key activities in the central nervous system. Cytoplasmic polyadenylation, one mechanism of controlling translation, is driven by cytoplasmic polyadenylation element binding proteins, called CPEBs. CPEB3 (cytoplasmic polyadenylation element binding protein 3) is a 698 amino acid protein that contains two RNA recognition motif (RRM) domains and, like other CPEB proteins, may play a role in the maturation of the central nervous system. CPEB3 exists as multiple alternatively spliced isoforms that are encoded by a gene which maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5 % of the human genome.