SNAPIN antibody (AA 51-136)

Catalog No. ABIN1386536

The Rabbit Polyclonal anti-SNAPIN antibody has been validated for ELISA, ICC, IF (cc), IF (p), IHC (p) and IHC (fro). It is suitable to detect SNAPIN in samples from Human.

Quick Overview for SNAPIN antibody (AA 51-136) (ABIN1386536)

Target: SNAPIN (SNAP-Associated Protein (SNAPIN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNAPIN antibody is un-conjugated

Application: ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-SNAPIN Antibody

Binding Specificity: AA 51-136

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SNAP25BP

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for SNAPIN

Target: SNAPIN (SNAP-Associated Protein (SNAPIN))

Alternative Name: SNAPIN/SNAP25BP

Background:

Synonyms: SNAP associated protein, SNAP-25-binding protein, SNAP-associated protein, SNAP25BP, SNAPAP, SNAPIN, SNAPN_HUMAN, SNARE associated protein snapin, SNARE-associated protein Snapin, Synaptosomal associated protein 25 binding protein, Synaptosomal-associated protein 25-binding protein, OTTHUMP00000035157.

Background: The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis of lysosome-related organelles) complex. Biochemical studies have identified additional binding partners. As part of the SNARE complex, it is required for vesicle docking and fusion and regulates neurotransmitter release. The BLOC-1 complex is required for the biogenesis of specialized organelles such as melanosomes and platelet dense granules. Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of Hermansky-Pudlak syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012].

Gene ID: 23557

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis