ATP13A2 antibody (AA 1001-1080)

Catalog No. ABIN1387850

The Rabbit Polyclonal anti-ATP13A2 antibody has been validated for ELISA, IF (cc), IF (p), IHC (fro), IHC (p) and ICC. It is suitable to detect ATP13A2 in samples from Rat.

Quick Overview for ATP13A2 antibody (AA 1001-1080) (ABIN1387850)

Target: ATP13A2 (ATPase Type 13A2 (ATP13A2))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP13A2 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-ATP13A2 Antibody

Binding Specificity: AA 1001-1080

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ATP13A2

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for ATP13A2

Target: ATP13A2 (ATPase Type 13A2 (ATP13A2))

Alternative Name: PARK9/ATP13A2

Background:

Synonyms: AT132_HUMAN, Atp13a2, ATPase type 13A2, CLN12, HSA9947, KRPPD, PARK9, Probable cation transporting ATPase 13A2, Probable cation-transporting ATPase 13A2, Putative ATPase, RP1-37C10.4.

Background: ATP13A2 is a 1,180 amino acid multi-pass membrane protein that belongs to the P5 subfamily of ATPases which play an important role in the transportation of inorganic cations. Expressed as multiple alternative spliced isoforms, ATP13A2 functions to catalyze the conversion of ATP to ADP and a free phosphate, thereby participating in the active transport of ions across cellular membranes. Defects in the gene encoding ATP13A2 are the cause of Kufor-Rakeb syndrome (KRS), a rare hereditary type of Parkinson?s disease that exhibits juvenile onset and is characterized by neurodegeneration and dementia. The ATP13A2 gene maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8 % of the human genome.

Pathways: Ribonucleoside Biosynthetic Process