SYNM antibody (AA 501-650)

Catalog No. ABIN1387897

This Rabbit Polyclonal antibody specifically detects SYNM in ELISA, WB, IHC (p), IF (cc), IF (p) and IHC (fro). It exhibits reactivity toward Mouse and Ratand has been mentioned in 1 publication.

Quick Overview for SYNM antibody (AA 501-650) (ABIN1387897)

Target: SYNM (Synemin, Intermediate Filament Protein (SYNM))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYNM antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-SYNM Antibody

Binding Specificity: AA 501-650

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Desmuslin

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-SYNM antibody (ABIN1387897)

Bengoechea, Pittman, Tuck, True, Weihl: "Myofibrillar disruption and RNA-binding protein aggregation in a mouse model of limb-girdle muscular dystrophy 1D." in: Human molecular genetics, Vol. 24, Issue 23, pp. 6588-602, (2015) (PubMed).

Target Details for SYNM

Target: SYNM (Synemin, Intermediate Filament Protein (SYNM))

Alternative Name: Desmuslin

Background:

Synonyms: DMN, SYN, Synemin, Desmuslin, SYNM, KIAA0353

Background: Type-VI intermediate filament (IF) which plays an important cytoskeletal role within the muscle cell cytoskeleton. It forms heteropolymeric IFs with desmin and/or vimentin, and via its interaction with cytoskeletal proteins alpha-dystrobrevin, dystrophin, talin-1, utrophin and vinculin, is able to link these heteropolymeric IFs to adherens-type junctions, such as to the costameres, neuromuscular junctions, and myotendinous junctions within striated muscle cells.

Gene ID: 23336

UniProt: O15061