BPIFC antibody (AA 131-230)
Quick Overview for BPIFC antibody (AA 131-230) (ABIN1388022)
Target
Reactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 131-230
-
Cross-Reactivity
- Human
-
Predicted Reactivity
- Mouse,Rat,Cow,Sheep,Pig,Rabbit
-
Purification
- Purified by Protein A.
-
Immunogen
- KLH conjugated synthetic peptide derived from human BPIL2
-
Isotype
- IgG
-
-
-
-
Application Notes
-
WB 1:300-5000
ELISA 1:500-1000 -
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 μg/μL
-
Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
Preservative
- ProClin
-
Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
Storage
- 4 °C,-20 °C
-
Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
Expiry Date
- 12 months
-
-
- BPIFC (BPI Fold Containing Family C (BPIFC))
-
Alternative Name
- BPIL2
-
Background
-
Synonyms: BPIL 2, BPIL-2, bactericidal/permeability increasing protein like 2, BPC_HUMAN.
Background: Members of the bactericidal/permeability-increasing protein family have antimicrobial properties and bind lipophilic substances, therefore targeting gram-negative bacteria. The bactericidal permeability increasing protein (BPI) is an antibacterial and endotoxin-neutralizing molecule that is abundant in the granules of polymorphonuclear leukocytes (neutrophil granules). Sharing structural and sequence homologies with BPI, BPIL2 (Bactericidal/permeability-increasing protein-like 2) is a 507 amino acid secreted protein that contains the family?s common conserved feature of two cysteine residues that are critical for protein function. While BPIL2 is expressed in the basal layer of inflamed epidermis from psoriasis patients, it is not detected in normal skin.
-
Gene ID
- 254240
-
UniProt
- Q8NFQ6
Target
-
