PVRL4 antibody (AbBy Fluor® 647)

Catalog No. ABIN1388274

This anti-PVRL4 antibody is a Rabbit Polyclonal antibody detecting PVRL4 in WB. Suitable for Human, Mouse and Rat.

Quick Overview for PVRL4 antibody (AbBy Fluor® 647) (ABIN1388274)

Target: PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PVRL4 antibody is conjugated to AbBy Fluor® 647

Application: Western Blotting (WB)

Product Details anti-PVRL4 Antibody (AbBy Fluor® 647)

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Nectin 4

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PVRL4

Target: PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))

Alternative Name: Nectin 4

Background:

Synonyms: Ig superfamily receptor LNIR, Nectin 4, poliovirus receptor-related 4, PRR4, poliovirus receptor related 4.

Background: This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.

Gene ID: 59341

Pathways: Cell-Cell Junction Organization