FGFBP2 antibody (AA 121-220) (Biotin)

Catalog No. ABIN1390357

This Rabbit Polyclonal antibody specifically detects FGFBP2 in ELISA, IHC (fro), IHC (p). It exhibits reactivity toward Human.

Quick Overview for FGFBP2 antibody (AA 121-220) (Biotin) (ABIN1390357)

Target: FGFBP2 (Fibroblast Growth Factor Binding Protein 2 (FGFBP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGFBP2 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-FGFBP2 Antibody (Biotin)

Binding Specificity: AA 121-220

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FGFBP2/KSP37

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for FGFBP2

Target: FGFBP2 (Fibroblast Growth Factor Binding Protein 2 (FGFBP2))

Alternative Name: FGFBP2/KSP37

Background:

Synonyms: FGF-binding protein 2, FGF-BP2, FGFBP-2, FGFBP2, FGFP2_HUMAN, Fibroblast growth factor-binding protein 2, HBp17-related protein, HBp17-RP, Ksp37, 37 kDa killer-specic secretory protein.

Background: KSP37 is a 223 amino acid protein that is secreted into the extracellular space and belongs to the fibroblast growth factor-binding protein family. Expressed in serum, as well as in cytotoxic T lymphocytes and peripheral leukocytes, KSP37 is thought to be involved in lymphocyte-mediated immunity, possibly playing a role in the development of asthma. The gene encoding KSP37 maps to human chromosome 4, which encodes nearly 6 % of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.