TAS2R16 antibody (AA 147-182) (Biotin)

Catalog No. ABIN1392331

This Rabbit Polyclonal antibody specifically detects TAS2R16 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for TAS2R16 antibody (AA 147-182) (Biotin) (ABIN1392331)

Target: TAS2R16 (Taste Receptor, Type 2, Member 16 (TAS2R16))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAS2R16 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA

Product Details anti-TAS2R16 Antibody (Biotin)

Binding Specificity: AA 147-182

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TAS2R16

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for TAS2R16

Target: TAS2R16 (Taste Receptor, Type 2, Member 16 (TAS2R16))

Alternative Name: TAS2R16

Background:

Synonyms: TAS2R-16, T2R16, Taste receptor type 2 member 16, T2R16_HUMAN.

Background: T2R16 is a 291 amino acid multi-pass membrane protein that belongs to the G-protein coupled receptor T2R family. Acting in the oral cavity and the gastrointestinal tract, T2R16 is a gustducin-coupled receptor that is implicated in the perception of bitter compounds. T2R16 mediates responses to certain taste through PLC 2, a phospholipase C selectively expressed in taste tissue, and the calcium-regulated cation channel TRPM5. Expressed in a subset of gustducin-positive taste receptor cells of the tongue and epithelia, T2R16 confers bitter perception of salicin to non-taster mice. The gene that encodes T2R16 consists of 996 bases and maps to human chromosome 7q31. Chromosome 7 houses over 1,000 genes, comprises nearly 5 % of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The Lys-172 polymorphism in T2R16 is associated with genetic susceptibility to alcoholism.