LPPR4 antibody (AA 251-360) (AbBy Fluor® 350)

Catalog No. ABIN1393839

This anti-LPPR4 antibody is a Rabbit Polyclonal antibody detecting LPPR4 in WB, IF (cc) and IF (p). Suitable for Human.

Quick Overview for LPPR4 antibody (AA 251-360) (AbBy Fluor® 350) (ABIN1393839)

Target: LPPR4 (Lipid Phosphate Phosphatase-Related Protein Type 4 (LPPR4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LPPR4 antibody is conjugated to AbBy Fluor® 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-LPPR4 Antibody (AbBy Fluor® 350)

Binding Specificity: AA 251-360

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LPPR4

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for LPPR4

Target: LPPR4 (Lipid Phosphate Phosphatase-Related Protein Type 4 (LPPR4))

Alternative Name: LPPR4

Background:

Synonyms: Brain-specic phosphatidic acid phosphatase-like protein 1, KIAA0455, Lipid phosphate phosphatase-related protein type 4, Lppr4, LPPR4_HUMAN, Plasticity-related gene 1 protein, PRG-1.

Background: Phosphatidate phosphatases are a family of integral membrane glycoproteins that dephosphorylate a variety of lipid phosphates and play a role in signal transduction via the phospholipase D pathway. PAP-2 proteins function independently of Mg2+ and are insensitive to NEM (N-ethylmaleimide) inhibition. The lipid phosphates degraded by this family include ceramide 1-phosphate (C1P), sphingosine 1-phosphate (S1P), phosphatidic acid (PA) and lysophosphatidic acid (LPA). LPPR4 (lipid phosphate phosphatase-related protein type 4), also known as LPR4, PHP1, PRG1 or PRG-1, is a 763 amino acid multi-pass membrane protein that belongs to the PA-phosphatase related phosphoesterase family. Exclusively expressed in neurons, LPPR4 hydrolyzes lysophosphatidic acid (LPA) and facilitates axonal outgrowth during development and regenerative sprouting. LPPR4 exists as two alternatively spliced isoforms and is encoded by a gene located on human chromosome 1p21.2.