Snail + Slug (pSer246) antibody (Biotin)
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- Target
- Snail + Slug
- Binding Specificity
- pSer246
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- Biotin
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Application
- ELISA
- Cross-Reactivity
- Human
- Predicted Reactivity
- Mouse,Rat,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic phosphopeptide derived from human SNAIL around the phosphorylation site of Ser246
- Isotype
- IgG
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-
- Application Notes
- ELISA 1:500-1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
-
- Target
- Snail + Slug
- Background
-
Synonyms: SNAIL + SLUG phospho S246 + S251, SNAIL + SLUG phospho Ser246 + Ser251, SNAILSer246 + SLUGSer251, dJ710H13.1, MGC10182, Neural crest transcription factor Slug, Protein sna, Protein snail homolog 1, Protein snail homolog 2, Protein snail homolog, Slug homolog zinc finger protein, Slug zinc finger protein, SLUGH, SLUGH 1, SLUGH1, SLUGH2, SNA, Sna protein, SNAH, SNAI 2, snai1, SNAI1_HUMAN, Snai2, SNAI2_HUMAN, Snail 2, Snail homolog 1 Drosophila, Snail homolog 2, Snail2, WS 2D, WS2D, Zinc finger protein SLUG, Zinc finger protein SNAI1, Zinc finger protein SNAI2.
Background: This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin. SLUG is involved in epithelial-mesenchymal transitions (EMT) involving E-cadherin repression which is known to play an important role in tumor progression amd neural tube formation. SLUG also has antiapoptotic activity. Mutations in this gene may be associated with sporadic cases of neural tube defects (referenced from Entrez gene).
- Gene ID
- 6311
- UniProt
- O95863
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