NCS1 antibody (AA 1-50) (FITC)

Catalog No. ABIN1394438

The Rabbit Polyclonal anti-NCS1 antibody has been validated for WB, IF (p) and IF (cc). It is suitable to detect NCS1 in samples from Rat.

Quick Overview for NCS1 antibody (AA 1-50) (FITC) (ABIN1394438)

Target: NCS1 (Neuronal Calcium Sensor 1 (NCS1))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCS1 antibody is conjugated to FITC

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Product Details anti-NCS1 Antibody (FITC)

Binding Specificity: AA 1-50

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NCS1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for NCS1

Target: NCS1 (Neuronal Calcium Sensor 1 (NCS1))

Alternative Name: NCS1/Frequenin

Background:

Synonyms: 9430075O15Rik, A730032G13Rik, AI836659, DKFZp761L1223, FLUP, Frequenin, Frequenin homolog Drosophila, Frequenin homolog, Frequenin like protein, Frequenin, Drosophila, homolog of, Frequenin-like protein, Frequenin-like ubiquitous protein, Mfreq, NCS 1, NCS-1, ncs1, NCS1_HUMAN, Neuronal calcium sensor 1, Neuronal Calicum Sensor 1.

Background: NCS-1 (for neuronal calcium sensor-1, also designated frequenin) belongs to a highly conserved family of EF-hand-containing Ca++-binding proteins expressed mainly in neurons. NCS-1 is localized to neuronal cell bodies and axons throughout the brain and spinal cord. It is also expressed in glial cells and in neuroendocrine bovine adrenal chromaffin and PC12 cells. NCS-1 is a regulatory protein involved in Ca++-dependent exocytosis of synaptic vesicles and dense core granules. NCS-1 also functions in the voltage-independent autocrine pathway that negatively regulates non-L-type Ca++ channels.