Trace Amine Associated Receptor 8 (TAAR8) (AA 51-150) antibody (Biotin)

Catalog No. ABIN1394713

This Rabbit Polyclonal antibody specifically detects in WB, IHC (p), ELISA and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for Trace Amine Associated Receptor 8 (TAAR8) (AA 51-150) antibody (Biotin) (ABIN1394713)

Target: Trace Amine Associated Receptor 8 (TAAR8)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details

Binding Specificity: AA 51-150

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human G protein coupled receptor 102

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details

Target: Trace Amine Associated Receptor 8 (TAAR8)

Alternative Name: GPR102/TAAR8

Background:

Synonyms: G protein coupled receptor 102, G-protein coupled receptor 102, GPR102, TA5, TAAR8, TAAR8_HUMAN, TaR-5, TaR-8, TAR5, Trace amine assiciated receptor 8, Trace amine receptor 5, Trace amine receptor 8, Trace amine-associated receptor 8, TRAR5, GPCR GPR102.

Background: Trace amines are endogenous molecules structurally related to classical biogenic amines that are linked to psychiatric conditions. A family of G-protein coupled receptors referred to as trace-amine-associated receptors (TAAR) are activated by trace amines and are present in very low levels in mammalian tissue. TaRs contain several structural features that are similar to the rhodopsin -adrenergic receptor superfamily, including the positions of the seven transmembrane regions that provide common ligand-binding pockets as well as the short N- and C-terminal domains. TAAR proteins are potential targets for drugs of abuse, such as amphetamine and MDMA, as well as neuropsychiatric disorders including schizophrenia, depression, and attention deficit disorder.